What is Chronic Depression?
Chronic depressive disorder, or dysthymia, refers to a continuous, long-term form of depression that can last for years, often coming and going. Its ongoing nature may interfere with relationships and daily activities.
Chronic Depression Symptoms
Symptoms generally include feelings of hopelessness; loss of interest in daily activities; avoidance of social situations; low self-esteem or self-criticism; tiredness; and trouble concentrating or making decisions.
Clinically, a combination of medication and talk therapy can be effective in treating chronic depression.
Ketamine and Chronic Depression
Ketamine is a drug that has been around since the 1960s. It is commonly used in hospital emergency rooms as an anesthetic in setting broken bones for children, and it is also used in burn units.
For more than a decade, studies have reported that ketamine is also effective in reversing severe depression that is resistant to traditional anti-depressants. It is reputed to yield a quick antidepressant effect, by contrast to traditional drugs, which often don’t have an impact for a couple of weeks. It has also been shown to have a quick impact in chronic depression.
According to Bloomberg News, “Additional studies show that ketamine works by producing long-lasting changes in the brain, reversing neural damage caused by stress and depression and potentially decreasing inflammation and cortisol levels.”
Off-label use of ketamine as a treatment for chronic depression is on the rise, since its efficacy impresses numerous mental health professionals.